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Alcohol and Heart Disease Lecture given at the SMAB conference, Oslo in October 2000, by Hans Olav Fekjær. During the last two decades, several studies have shown a correlation between a low or moderate alcohol consumption and a reduced mortality from coronary heart disease and stroke. Most have been cohort studies, a limited number have been case-control. Over time, the studies have been refined, taking a larger number of potential confounders into account. Most studies now not only control for age, blood pressure, smoking and body mass index, but also for pre-existing diseases , cholesterol, .. And in approximately 80% of the studies, the statistical correlation between a low alcohol consumption and the reduced mortality has been demonstrated. In addition, possible mechanisms to mediate a beneficial effects have been established, although, admittedly, mechanisms in the opposite direction have ...

C L E V E L A N D C L I N I C J O U R N A L O F M E D I C I N E V O L U M E 7 0 • N U M B E R 9 S E P T E M B E R 2 0 0 3 745 EPRESSION seems to be a bona fide risk fac- tor for coronary artery disease . Statistical associations exist between depression and the development of coronary disease , and the prog- nosis is worse for coronary patients with depres- sion. Moreover, there are plausible physiologic mechanisms to explain the link. Although we do not know if treating depression can improve one’s coronary prog- nosis, it can certainly make the patient feel better. Yet, depression is undertreated in coro- nary patients. This paper reviews the surprising associa- tion of depression with coronary artery disease and explains the possible mechanisms leading to major adverse cardiac events. It also discuss- es treatment options, including drug interac- tions ...

heart heart disease WOMEN AND HEART DISEASE House of Representatives - February 26, 2003 Mr. Speaker, February is American Heart Month, which attempts to educate people on the dangers of heart disease and other heart related medical problems. It is in recognition of this important issue and the way in which it affects women that I come to the floor to speak today. One in two American women will eventually die of heart disease or stroke. One in Two! This is compared with one in twenty-seven who will die of breast cancer. This is a stark and alarming fact that most women have not heard. For my state, that means that every year around 11,500 women in Tennessee die from causes brought on by Heart Disease . But there are things that women can do to decrease their risk. The first of these is to stop smoking, which is the single greatest risk factor for a heart attack in women. Check ...

n engl j med 348;23 www.nejm.org june 5, 2003 c o r r e s p o n d e n c e 2359 tween frequent ventricular ectopy during recovery and the type of recovery protocol used for the pre- diction of death (P for interaction, 0.97). Michael S. Lauer, M.D. Cleveland Clinic Foundation Cleveland, OH 44195 lauerm@ccf.org Joseph P. Frolkis, M.D., Ph.D. University Hospitals of Cleveland Cleveland, OH 44106 Eugene H. Blackstone, M.D. Cleveland Clinic Foundation Cleveland, OH 44195 Carcinoid Heart Disease to the editor: Møller et al. (March 13 issue) 1 ad- dressed the topic of the progression of carcinoid heart disease . Serial echocardiographic studies were available for 71 of the 273 referred patients. The median level of urinary 5-hydroxyindoleacetic acid (5-HIAA) excretion ...

Carcinoid Heart Disease The Role of Urinary 5-Hydroxyindoleacetic Acid Excretion and Plasma Levels of Atrial Natriuretic Peptide, Transforming Growth Factor- and Fibroblast Growth Factor Johanna M. Zuetenhorst, M.D. 1 Johannes M. G. M. Bonfrer, M.D., Ph.D. 2 Catharina M. Korse 2 Rob Bakker, M.D. 3 Harm van Tinteren, MSc. 4 Babs G. Taal, M.D., Ph.D. 1 1 Department of Gastroenterology, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. 2 Department of Clinical Chemistry, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. 3 Department of Cardiology, Slotervaart Hospital, Amsterdam, The Netherlands. ...

Critical Health Indicators – Michigan Department of Community Health Vital Statistics Indicators Heart Disease Deaths Heart Disease Death Rates Michigan Residents 322.5 335.3 324.9 316.7 309.3 294.4 296.5 280.3 287.6 288.1 0 50 100 150 200 250 300 350 400 1992 1993 1994 1995 1996 1997 1998 1999* 2000* 2001* Year * Death data based on ICD-10 coding. See Technical Notes for detailed explanation on ICD coding changes. Source: Division for Vital Records and Health Statistics, MDCH How are we doing? Heart disease remains the leading cause of all deaths in Michigan and the second leading cause of Years of Potential Life Lost (YPLL) for people below the age of 75. Heart disease also continues to be ...

G U I D E L I N E S F O R C A R E F O R P E O P L E W I T H H E A R T D I S E A S E Risk Factor Management Many deaths from heart disease can be prevented by knowing and managing risk factors that can lead to a heart attack. If you have a family history of heart disease , have high blood pressure, smoke, have high cholesterol, have diabetes, or are overweight, you may be at increased risk for heart disease or a heart attack. Even though some risk factors, like family history, cannot be changed, you can change many others. Know your risk factors and talk with your health care team at each visit about reducing your risk of heart disease . Smoking Cessation Cigarette smoking is the number-one risk factor for heart and blood vessel disease .When you quit smoking, your risk of heart disease goes down. One year after you quit, your risk of ...

__ STATE OF CALIFORNIA HEALTH AND HUMAN SERVICES AGENCY DEPARTMENT OF HEALTH SERVICES Gray Davis, Governor Grantland Johnson, Secretary Diana M. Bontá, R.N., Dr. P.H., Director HEART DISEASE DEATHS IN CALIFORNIA, 1999 By Daniel H. Cox Introduction Heart disease has historically been the leading cause of death in the United States and in California. In 1996, 21 million cases of heart disease were reported in the United States and in 1999, 4.5 million hospital discharges were attributed to heart disease . 1 There were 725,192 heart disease deaths in the United States in 1999. 2 This report presents data on heart disease deaths in California during 1999, and provides analysis of crude and age-adjusted death rates for California residents by sex, age, race/ethnicity, and county. The definition of heart ...

August 2002 Preventive Measures for Ischemia Heart Disease (IHD) A new study in the August issue of the American Journal of Clinical Nutrition has found that those at risk for ischemia heart disease (IHD) can benefit greatly from an increased intake of fish and/or dietary supplementation of omega-3 fatty acids. This study adds to previous research on the benefits of omega-3 fatty acids. "Ichemia" basically means that there is insufficient blood and oxygen getting to the heart which has a negative effect on what's called systemic arterial compliance (SAC), a measure of the degree of artery elasticity. Increased stiffness in the large arteries can lead to hypertension and elevate pulse pressure - both of which increase the risk of coronary heart attack. Symptoms can run the gamut from chest pains or tightness and pressure under the sternum to heart beat palpitations, irregular ...

Women and Heart Disease Women and Heart Disease Globally, 1 in 3 women die from heart disease , 1 in 6 die from stroke, 1 in 9 develop breast cancer and 1 in 25 die from breast cancer 1 . Experience in developed countries such as Australia suggests that the importance of cardiovascular disease , including heart disease , is often overlooked. The risk of developing cardiovascular disease increases with age so there is a need for increased awareness of the importance of cardiovascular disease as a major public health issue for older women. Table 1: Deaths from cardiovascular diseases in Australia, 2000. Cause of Death Males Females All cardiovascular diseases 23,774 25,967 Coronary heart disease 14,052 12,469 Heart failure 982 1,662 Hypertensive disease 449 ...

Positive steps to reduce your risk of heart disease Your heart needs care for life. A healthy heart is about enjoying a healthy lifestyle and making this a part of your everyday life. It is also about taking positive steps to reduce risk factors. Everyone can do something to help prevent heart disease , including people who already have heart disease or who have had a heart event. The good news is that if you lead a healthy lifestyle, as outlined below, you can reduce your risk of developing heart disease . The best ways to reduce the risk of developing heart disease , and to help prevent it getting worse if it already exists is to reduce or remove the risk factors over which we have some control. To do this, have ongoing heart disease risk assessments with your doctor and lead a healthy lifestyle as outlined below. Being male, increasing age and having a family ...

Ohio Plan to Prevent Heart Disease & Stroke 2002 — 2007 March 2003 1st Edition Page 2 Ohio Plan to Prevent Heart Disease & Stroke 2002 — 2007 Page 3 Ohio Plan to Prevent Heart Disease & Stroke 2002 — 2007 i Although bioterrorism, anthrax, and smallpox steal the headlines, heart disease and stroke continue to be the number one and three causes of death in Ohio and the nation. Reducing morbidity and mortality from cardiovascular disease is a task of such magnitude that only a combined effort of many organizations and individuals will result in success. This plan illustrates the result of such a cooperative effort. Public and private sector organizations; educational institutions and professional organizations; and faith-based health services and major medical facilities ...

1 Heart Disease and Stroke in Rural America MODELS FOR PRACTICE FOCUS AREA: HEART DISEASE AND STROKE Program Name: Western Maine Center for Heart Health Location: Farmington, Maine Problem Addressed: Heart Disease and Stroke Healthy People 2010 Objective: 12-1, 12-11, 12-15 Web Address: http://www.fchn.org (click “ Heart Health”) and http://www.franklinscorekeeper.org SNAPSHOT The Western Maine Center for Heart Health (WMCHH) reflects collaboration between the county’s 70-bed hospital, doctors, business leaders, and community residents. The center, which is a department within Franklin Memorial Hospital, is composed of four main divisions: HeartWarmers (for highest risk people with cardiovascular disease ), Franklin ScoreKeeper (for individual children and adults at all risk levels), Research and Development, and Consultation and ...

Life course perspectives on coronary heart disease , stroke and diabetes WHO/NMH/NPH/02.1 ORIGINAL: ENGLISH DISTR.: GENERAL Ageing and Life Course Department of Noncommunicable Diseases Prevention and Health Promotion Noncommunicable Diseases and Mental Health Cluster WORLD HEALTH ORGANIZATION The evidence and implications for policy and research ACCUMULA TED NCD RISK AGE Page 2 The risk of noncommunicable diseases accumulates with age and is influenced by factors acting at all stages of the life span. The main factors at different stages of life include the following: 1 Fetal Life fetal growth, maternal nutritional status, socioeconomic position at birth 2 Infancy and Childhood growth rate, breastfeeding infectious diseases , unhealthy diet, lack of physical activity, ...

1 Task Force on Heart Disease and Stroke Prevention First Meeting October 19, 2001 10:00 a.m. - Noon Task Force Members present - Bo Bowen, Larry Calvert, Clay Hays, M.D., Samantha heard, Debbie King, Pharm D., James McIlwain, M.D., Marcella McKay, Ed Thompson, M.D., Evelyn Ricks Walker, M.D., Joyce Vaughn, Jim Wadlington, Sharon Wyatt, R.N., Ph.D. Not present - Jim Barnett, M.D. (State Representative), Joe Blackston, M.D., Sam Cameron, Nolan Mettetal (State Senator), Robert Pugh. Noted guests - Alan Penman, M.D., Ellen Jones, Rise Hicks, Sherry Hill, Mary Helen Conner, Sandie Browne, James (not legible), Dr. Charles Guess, Beryl Polk, Melanie Bowman, Laurie Walters, Susan Loyd, Brain Tharp, Victor Sutton, Jody Henderson, Cheryl Russvin, Rebecca Wood. Victor Sutton, Director , Division of Health Promotion, opened the meeting by welcoming the members of the task force and recognizing Mississippi ...

21. Heart Disease & Stroke 21 Goal: Page 2 Healthy Alaskans 2010 - Volume I 21-2 21. Heart Disease & Stroke 21 21. Heart Disease & Stroke identifi cation and treatment of heart attacks and strokes; and prevention of identifi cation and treatment of heart attacks and strokes; and prevention of identifi cation and treatment of heart attacks and strokes; and prevention of recurrent cardiovascular events. Indicator Alaska Data Source U.S. Baseline Alaska Baseline Alaska Target Year 2010 1 Reduce coronary heart disease (ICD-10: 120-125) deaths (per 100,000 population). ABVS 186.4 (2000) 131.5 (1999) 120 Alaska Native ABVS 123.3 (1999) 120 2 Increase ...

1 I NSIDE T HIS I SSUE Visit our new patient education website at http://www.palo-alto.med.va.gov/patienteducation/ patienteducation.htm Coping with Stress ..2 Headache Trivia.2 Unplanned Weight Loss ..3 Headache Trivia Answers ..3 Veterans Affairs Palo Alto Health Care System ? Patient Education Newsletter ? Summer 2003 Recipe for Health ?Promoting Good Health Through Information? Summer Vegetable Spaghetti This lively vegetarian pasta dish contains no added fat or oil, is low in cholesterol, and is good hot or cold. 2 C small yellow onions, cut in eighths 2 C chopped, peeled, fresh, ripe tomatoes (~1 lb) 2 C thinly sliced yellow and green squash (~1 lb) 1- 1/2 C cut fresh green beans (~1/2 lb) 2/3 C water 2 Tbsp minced ...

How to prevent heart disease What is heart disease and why should I be concerned? Heart disease is a name given to a variety of conditions that affect the performance of the heart . Important examples of heart disease include: • angina, in which there is poor blood circulation to the heart , • heart attack, in which there is death of part of the heart muscle, and • arrhythmia, in which the rate or rhythm of the heart beat is abnormal. In the UK, heart disease kills more people, both men and women, than any other disease . One British adult dies of heart disease every two minutes. Your heart is the engine that drives your body. It is a powerful muscle that pumps blood to your entire body, providing the oxygen and nutrients that you need to live. The average human heart works at a rate of 100,000 beats a day ...

Editorial Mayo Clin Proc, June 2003, Vol 78 684 The US Food and Drug Administration (FDA), the phar- maceutical industry, and others attempted to inform the public of the relative risk of PAVHD. On the FDA’s MedWatch Web site, a letter from Eli Lilly and Company informed readers that since 1989 an estimated 500,000 people have been treated with pergolide. Of these, “valvulopathy has been reported in less than 0.005%.” 4 This upper-limit figure (0.005% of 500,000) would repre- sent some 25 patients, a number clearly in excess of the 3 patients reported by Pritchett and colleagues. 1 Because the Proceedings helped bring the issue of PAVHD to the consciousness of many, the journal felt a responsibility to help determine what is and what is not known about the anomaly. The journal contacted the FDA to determine the number of patients it had registered with ...

Women and Heart Disease Hi, I’m Beth Ruyak. Here’s a question for women: Are you more afraid of heart disease , or of cancer? Now the startling news is that heart disease actually kills twice as many women in the United States as all cancers combined. And if that’s not enough to make you pay attention, there’s this, the number of heart disease deaths is increasing. FOR DECADES, HEART DISEASE HAS REMAINED SECURELY PERCHED AT THE TOP OF AMERICA’S "MOST DEADLY DISEASES " LIST. THE DATA USED TO COMPILE SUCH LISTS HAS, UNTIL RECENTLY, BEEN BASED ON THE CASE STUDIES OF MEN. NOW AS RESEARCHERS FACTOR WOMEN INTO THE EQUATION, ONE STARTLING FACT IS BECOMING CLEAR: HEART DISEASE IS A MUCH GREATER AND DEADLIER HEALTH THREAT FOR WOMEN THAN IT IS FOR MEN. Dr. Amparo Villablanca, Director, Women’s Cardiovascular Health Program " Heart disease in women is a huge problem. ...

Depression and Heart Disease EXERCISE, EAT RIGHT AND DON'T SMOKE. THOSE ARE THE INGREDIENTS FOR A HEALTHY HEART , BUT THERE'S ONE MORE: KEEP SMILING. BECAUSE YOUR MOOD CAN EFFECT YOUR HEART , AND IF YOU ARE OVER 65, THERE'S NEW EVIDENCE THAT SUGGEST HEART DISEASE AND YOUR MENTAL STATE ARE CLOSELY RELATED. AH, THE GOLDEN YEARS. THEY CAN SYMBOLIZE RETIREMENT, RELAXATION AND ENJOYING THE GOOD LIFE. THOSE YEARS AFTER 65 CAN ALSO MARK A CHANGE IN YOUR HEALTH. THERE'S NEW EVIDENCE THAT OLDER ADULTS MAY HAVE A UNIQUE MIND-BODY CONNECTION, AND THEIR MENTAL ATTITUDE CAN GREATLY AFFECT THEIR HEART HEALTH. Dr. Abraham Ariyo: "It's the number one cause of death among women, it's the number one cause of death among men, it's the number one cause of death regardless of the race, regardless of the age." DR. ABRAHAM ARIYO IS TALKING ABOUT HEART DISEASE . AS A CARDIOLOGIST AT THE UC DAVIS MEDICAL ...

Early Signs of Heart Disease Heart disease continues to be the number one killer of Americansand while you may think of heart attacks and high cholesterol as adult only issues, they’re not. Children are at risk, too. A TEENAGER’S LIFE CAN BE FULL OF NUMBERS. GRADE POINT AVERAGE: 3.4, NUMBER OF YEARS PLAYING SOCCER: 5, NUMBER OF TIMES ON THE DEAN'S LIST: 2..THEN HOW ABOUT THIS FOR A NUMBER: TOTAL CHOLESTEROL: 225 HEART DISEASE ISN'T AN ADULT ONLY ISSUE, BUT TALK TO ANYONE UNDER THE AGE OF 25 AND IT SEEMS THAT CORONARY ARTERIES AND HYPERTENSION ARE THE FURTHEST THINGS FROM THEIR MINDS. WE SAT DOWN WITH A GROUP OF TEENS TO SEE IF THEY EVEN THINK ABOUT HEART DISEASE Girl "I never do.” First Boy “No.” Second Boy “Nope!" Dr. Jeanny Park/Pediatric Cardiologist "They can be in the beginning stages of developing clogging in their coronary or heart ...

Heart Disease Predictor Beth Ruyak/Host Are you at risk for heart disease ? If you're health-conscious, you already know that along with weight and blood pressure, blood cholesterol is an important predictor of your risk. But scientists have recently discovered another indicator that may also be very important.” It's called C-reactive protein and while you may not have heard of it, doctors across the United States are ordering it for their patients.” Dr. Ezra Amsterdam/ Director/Cardiac Care Unit, UC Davis Heart Center “Good afternoon Mr. Durnesky. How are you doing?” Mr. Durnesky/Patient “Hi, I’m doing well, doctor. Thank you.” DR. EZRA AMSTERDAM, DIRECTOR OF THE CARDIAC CARE UNIT OF THE UC DAVIS HEART CENTER, BELIEVES C-REACTIVE PROTEIN LEVELS PROVIDE IMPORTANT NEW INFORMATION FOR PATIENT CARE. Dr. Amsterdam "The c-reactive protein adds to the information that the ...

© Lifestyle Medicine Institute Western Lifestyle Disease I have drawn two compelling observations from my service as the pro- gram director of two national cholesterol conferences and my participa- tion in three others over the past decade. First, a great deal is known about what factors are responsible for causing coronary artery disease (CAD) and what populations are vulnerable. Second, the present C O R O N A R Y H E A LT H I M P R O V E M E N T P R O J E C T Eliminating Heart Disease Caldwell Esselstyn, Jr., MD, Cleveland Clinic This major review article appeared in the fall 2001 issue of Preventive Cardiology .* Dr. Caldwell Esselstyn, an eminent surgeon, who turned into a lifestyle interventionist, is now a preventive cardiology consultant at the well-known Cleveland Clinic. He not only reviews the evi- dence for a needed change in our national diet, but ...

12 Heart Disease and Stroke Co-Lead Agencies: Centers for Disease Control and Prevention National Institutes of Health Contents Goal..Page 12-3 Overview Page 12-3 Issues and TrendsPage 12-3 Disparities.Page 12-5 Opportunities ..Page 12-7 Interim Progress Toward Year 2000 Objectives .Page 12-14 Healthy People 2010—Summary of Objectives ..Page 12-15 Healthy People 2010 Objectives .Page 12-16 Heart Disease ..Page 12-16 Stroke ..Page 12-19 Blood PressurePage 12-20 Cholesterol Page 12-25 Related Objectives From Other Focus Areas ..Page 12-29 TerminologyPage 12-30 References.Page 12-33 Page 2 Page 3 Heart Disease and Stroke Page 12-3 Goal Improve cardiovascular health and quality of life through the prevention, detection, and treatment ...

Common Medical Diseases (II) Congenital Heart Disease _ The Eleventh Health Conference 28 State of the Art: Congenital Heart Disease 2002 Daphne Hsu, M.D. The following is a summary from the Power Point slides of Dr. Hsu's presentation New Advances in Pediatric Cardiology Management of the infant with congenital heart disease Fetal enchocardiography Infant surgery Heart transplantation Hypoplastic left heart syndrome Interventional Cardiology Fetal Ultrasound Cardiac development 6 weeks gestation: heart chambers, great arteries formed. 14 weeks: major cardiac defects can be detected by ultrasound. 22-24 weeks: most common time for abnormalities to be identified. Cardiac screening 4 chamber view 2 great arteries Fetal Echocardiography Ventricular hypoplasia Tricuspid atresia ...

12 Heart Disease and Stroke Heart Disease 12-1 Coronary heart disease (CHD) deaths 12-2 Knowledge of symptoms of heart attack and importance of calling 911 12-3 Artery-opening therapy 12-4 Bystander response to cardiac arrest 12-5 Out-of-hospital emergency care 12-6 Heart failure hospitalizations 12-6a 65 to 74 years 12-6b 75 to 84 years 12-6c 85 years and older Stroke 12-7 Stroke deaths 12-8 Knowledge of early warning symptoms of stroke Blood Pressure 12-9 High blood pressure 12-10 High blood pressure control 12-11 Action to help control blood pressure 12-12 Blood pressure monitoring Cholesterol 12-13 Mean total blood cholesterol levels 12-14 High blood cholesterol levels 12-15 Blood cholesterol screening ...

lion Program Project Grant (PPG). The grant was awarded in August by the National Heart , Lung and Blood Institute. Project One, led by Nadler, continues and advances Nadler’s research under an earlier PPG, which involved 12- lipoxygenase (12-LO), an inflammation-inducing enzyme that sits in blood vessel walls and becomes activated when exposed to high levels of sugar or insulin in the blood. “We believe the inflammation is what is tying diabetes and heart disease together,” says Nadler. 15 WINTER 2002 Helix n the United States, an estimated 16 mil- lion people have diabetes, according to the American Diabetes Association. These individuals are up to four times more likely to develop heart disease , primarily ath- erosclerosis, than other people. Furthermore, says Jerry Nadler, M.D., head of the Division of Endocrinology and Metabolism at UVa, ...

International Task Force for Prevention of Coronary Heart Disease Last update: Scientific News Literature Up-date since 2002 Observational Studies Prediction of risk of coronary events in middle-aged men in the Prospective Cardiovascular Münster Study (PROCAM), using neural networks. Int J Epidemiol 2002;31:1253-1262 Intervention trials indicate that about one in three coronary events can be prevented by 5 years of lipid-lowering treatment. This analysis suggests that use of the multi-layer perceptron to identify high-risk individuals as candidates for drug treatment would allow prevention of 25% of coronary events in middle-aged men, compared to 15% and 11% with logistic regression and the probabilistic neural networks, respectively. Abstract Years of life lost due to obesity JAMA 2003;289:187-193 Obesity appears to lessen life expectancy ...

Mark R. Geier, M.D., Ph.D. David A. Geier Introduction Abstract In this study, we evaluated doses of mercury from thimerosal-containing childhood immunizations in compari- son to US Federal Safety Guidelines and the effects of increasing doses of mercury on the incidence of neurodevelopment disorders and heart disease . This study showed that children received mercury from this source in excess of the Federal Safety Guidelines for the oral ingestion of methylmercury. Our analyses showed i n c r e a s i n g r e l a t i v e r i s k s f o r neurodevelopment disorders and heart disease with increasing doses of mercury. This study provides strong epidemiological evidence for a link between mercury exposure from thimerosal-containing childhood vaccines and neurodevelopment disorders. Many sources now confirm an autism epidemic in ...